An independent regulatory affairs consultant with 20 years of experience working in the pharmaceutical industry, Robert Gadimian serves as president of Perceptive Regulatory Consulting, California. Robert Gadimian is actively involved in supplement research for common skin problems like acne.
Acne is a skin problem that can present with whiteheads, blackheads, rashes, inflammation, and sometimes deep lesions in some areas of the skin where oil-producing glands can be found. Acne can be mild, moderate, or severe. In severe acne, a person can suffer permanent scarring of the skin, which may be embarrassing. Generally, multiple factors play an important role in a person’s susceptibility to acne. These include:
1. Genetic predisposition – Genes can contribute to an assortment of factors that can cause acne or a person’s susceptibility to it. For instance, hormones, which are products of genes, can play an important role in acne formation.
2. Hormones – Significant or rapid hormonal fluctuation can cause acne. While this is common during adolescence (where sex hormones boost rapidly), women who are pregnant, in premenopause, or using hormonal birth control can have rapid hormonal fluctuation.
3. Follicular hyperkeratinization – Follicular hyperkeratinization refers to the abnormal shedding of skin cells near pores’ openings. When this occurs, the cells may clog the pore and get inflamed by oils and other substances that otherwise would have been excreted through the opening.
4. Bacteria – Propionibacterium acnes, a bacterium, can grow abnormally on the skin and cause inflammation and skin damage – acne. It can also trigger other acne risk factors like follicular hyperkeratinization.
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